The invention provides a process for preparing 11 \u03b2-hydroxy steroid dehydrogenase type 1 inhibitors of formula 2 via a catalyzed reaction between a compound of formula 1 and a compound of formula R2LG in the presence of base:where R1, R2, X, Y, and LG are described in the specification. The voltage change detecting element detects a change of a voltage between a collector and an emitter or between a drain and a source of the driving element. Target items of interest to a salesperson are defined and a salesperson is associated with a customer. The sealed wire assembly includes a body having an outer surface defining a groove and a plurality of wires sealingly passing through the body.