Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer. Then, a nitride stack comprising a slow-etch nitride layer disposed between two fast-etch nitride layers is deposited in the cavity. This process makes it possible to improve the dielectric breakdown resistance of a copper interconnection formed by the damascene method. In a 3D display mode, two adjacent driving electrodes in the liquid crystal lens are respectively driven at a first time period and a second time period. In particular, the present devices and method relate to removal of the occluding material from the blood vessels as well as other body lumens. Preferably, the capacitor pre-charge test is performed when the ignition is switched ON and the capacitor discharge test is performed when the ignition is switched OFF.