A system of controlled translocation of macromolecules by gel electrophoresis employs a funnel nanopore structure. The present system includes a hybrid parser that employs both a lightweight parser and a heavy weight parser to parse a markup file. A therapeutic agent is disposed upon at least one portion of at least one lateral protrusion. During majority of symbols of an almost blank subframe of a base station, no signal is transmitted by the base station or signals are transmitted at an almost blank subframe power level that is different from a transmit power during a non-almost blank subframe.