Systems and methods enable adaptive, single bit-timeslot granular digital multiplexing capable of automatically and dynamically selecting an appropriate input bit from a set of alternative input ports, based on a current status of the alternative inputs. In some embodiments, the throat plates andor saws include at least one securement mechanism adapted to secure and prevent inadvertent removal of the throat plate from the throat of the saw. The laser hence can emit either a single lasing wavelength or a multiple of lasing wavelengths and is very suitable for swept-source OCT applications. The TSID is validated and classified. The process comprises selectively acylating hydroxyl at the 1-position and 11-position of a compound represented by formula B1 through one to three steps with an acylating agent in the presence or absence of a base.