An intelligent transmitter module includes a CDR circuit for equalizing and retiming an electrical data signal, a driver for generating a modulation signal andor performing waveform shaping of the equalized and retimed signal, and an optical transmitter configured to emit an optical signal representative of the data signal. The thermal therapy device can comprise a head pad, eye pads, a knee pad, an anklefoot pad, an elbow pad, or a neckshoulder pad. The invention also provides compositions and methods for treating cell proliferative diseases and conditions. A cash dispenser can be operated to dispense cash to a machine user in exchange for a deposited check.