The disclosure provides in one embodiment for a fastener comprising a cylindrical shaft, a head attached to the shaft, and two or more external longitudinal threadforms, where each threadform comprises a plurality of spaced protrusions forming a separate sinusoidal path around the shaft. Methods for inhibiting inflammatory disease cells as well as other cathepsin expressing cells in a subject with a cathepsin inhibitor or inhibitors are also within the present invention. The overcap may be formed from a multilayered coextruded sheet having a top layer of polymer material and a drying agent layer mixed with a polymer material. The optical component is constructed to operate as a first optical filter for light propagating between the optical ports of the first pair and is constructed to operate as a second optical filter for light propagating between the optical ports of the second pair.