The present invention is a high efficiency permanent magnet machine capable of maintaining high power density. The mixer receives water through a water inlet with water exhibiting high velocity and associated hydrodynamic force. Each contactor is constructed so that each includes multiple contact assemblies that may be independently controlled to open and close. An in situ bone anchor cell growth assembly includes the bone anchor and a manifold encompassing the neck portion so as to form a seal therebetween and a route of fluid communication between a manifold inlet and at least one of said plurality of channels. The reforming zone effluent and the isomerization zone effluent are each separated to form a light ends stream and a product stream.