This invention is a novel pharmaceutical composition comprising flurbiprofen or a pharmaceutically acceptable salt thereof in combination with an \u03b1-2 adrenergic receptor agonist or a gamma-aminobutiric acid receptor agonist with anti-inflammatory, analgesic and myorelaxant activity. The light coupler of the invention includes a plurality of light input terminals, a plurality of light output terminals, a plurality of half mirrors, and an optical wave guide connecting the plurality of the light input terminals, the plurality of the light output terminals and the plurality of the half mirrors. Each organic electroluminescent element flashes independently from the other organic electroluminescent elements. One recombinant clone expressed high level of Sp42 with an estimated 0.