Apparatuses and methods for applying laser energy for therapeutic purposes are disclosed. The method and apparatus uses the uplink quality indication channel for determining the downlink channel response, or uses round trip pilot relay channel sounding. Ethanol is optionally included in the formulation which is adapted for use in a body for the treatment of cancer, A formulation method is disclosed and includes the step of mixing an acid with a carrier material, such as polyethoxylated castor oil, to form a carrier solution after which paclitaxel is added in an amount such that the resulting pH is less than 8. This structure enables improvement in operation performance without increasing the layout area in the case where a DRAM cell is formed in a SOI structure.