The invention relates an additive for improving antioxidant capabilities in a lubricating composition, where the lubricating composition is based on a major amount of a lubricating oil and 0. The composition comprises an osteoinductive or osteopromotive biological factor embedded in a carrier slurry. A portion of the resilient element is separated from the dielectric material, and a portion of the resilient element is in contact with the dielectric material. In order to use the toothbrush, first the locking member is removed. Two pivot rods extend outwardly from opposite ends of the crank holder, and are rotatably received in two corresponding slots defined in two front posts. The quinazoline derivatives of Formula I are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, and, for example, EGFR tyrosine kinase.