A loop-filtering method for reducing quantization effect generated when an image data is encoded and decoded, and an apparatus therefor. Progressive kidney disease is treated by administering an iron chelator to humans. A network interface intercepts the reconfigure command and terminates a communication link through which the given host computer communicates to access the network. When the value of N1, N2 or is greater than a threshold counting number Cth, a detectable induced signal occurring in a sensing area is inferred. Each prong or spline is adjacent with at least two other prongs or splines. It also provides for the use of the cDNA, fragments, complements, and variants thereof and of the encoded protein, portions thereof and antibodies thereto for diagnosis and treatment of Crohn’s disease.