The invention relates to a method of cooling a metal strip traveling through a cooling section in a continuous heat treatment line. More particularly, the centrifugal clarifier contains a feed port that allows a liquid-solid mixture to be continuously fed into the device wherein the solid is sedimented by rotation of the separation chamber and the clarified liquid is released into an outside receptacle through an effluent port. The grouping of similar cellular response profiles allows the correlation between agent and mechanism, thus allowing for the identification of potential therapeutic applications of agents or further study of cellular responses or mechanisms.