A semiconductor device which can prevent an operation thereof from being uncontrollable to obtain a high reliability, and can be manufactured easily and can reduce a manufacturing cost. A second clamshell portion is coupled to the first clamshell portion about a fold axis. Bit lines to which the memory elements of all planes are connected are oriented vertically from the substrate and through the plurality of planes. The invention further provides therapeutic and diagnostic methods of use of the vectors, pharmaceutical formulations comprising the vectors, methods of making the vectors and transformed cells comprising the vectors. Of course, many alternatives, variations and modifications are possible without departing from this embodiment.