A shielded cable assembly that receives a shielded cable therein and includes an isolator or spacer block having a bore and a spring having a fixed portion disposed about the isolator and a resilient portion extending into the bore. The substrate is constituted by a metal substrate and a porous Al anodized film. Mounted on a movable support, the manifold may be brought into and out of fluid communication with a storage block comprising the plurality of reagents.