Residual, refractory or relapsed cancer is treated by immunostimulation in the presence of allogeneic immune effector cells, optimally in combination with radiation therapy. This analog control may be provided by an analog loop containing differential amplifiers that set the resolution limit of the output driver circuit. The method includes the step of forming an incubation mixture comprising the solution containing the lantibiotic and a proteolytic enzyme, and incubating the mixture under conditions optimized for selective proteolytic activity. A first portion of the pin extends through the first and second pin holes, and a second portion of the pin is arranged in the second region in the groove.