The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen compounds of general formula, methods for their preparation, and compositions comprising these compounds as well as their use for the treatment or prophylaxis of various disorders in humans or animals. The platforms includes at least one surface. A read circuit is provided that is capable of reading a logical state of a predetermined memory cell by differentiating a non-integrated first reference value from a non-integrated second reference value. , as compared to corresponding compositions containing the same peptide active therapeutic agent without associated ELPs. The system provides the user with a plurality of suffix selections to accept, reject or otherwise sort the different e-mail messages. There is also provided a lithium-ion secondary battery with such a negative electrode.