The present invention relates to a plate type speaker adapted to radiate sound by transforming horizontal vibration for vibrating a side of a diaphragm into vertical vibration of the diaphragm. An end piece which is a conductive member is connected to the conductive thread. The present method can be applied to any other organisms. The alternate route includes a third node as an upstream node of the first node. The invention is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty alcohols, long-chain fatty acids, and long-chain fatty esters.