The present invention relates to a composition comprising an immortalized cell line which is deficient in the expression of one or more gene of the intrinsic apoptotic pathway, selected from the group consisting of Bax, Bak, and mixtures thereof. The applying of the programming pulse includes applying a quantity of energy to the phase change material to drive at least a portion of this material above a melting energy level. The body connection region is disposed in the deep well region to connect the body regions. The system extracts an ambient noise signal representative of the ambient noise in the environment from the total sound signal in response to the total sound signal and to a reference signal derived from the electrical sound signal. The method according to the invention is characterized in that on analyzing characteristics of the reflection signals a course of a difference frequency spectrum formed by transmission frequency and reflection frequency spectrum is analyzed resolved by altitude levels.