Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications. The optical core has a central reinforcing element, a polymer layer, a plurality of optical fibres incorporated in the polymer layer and a thin sheath which covers the polymer layer. One or more reflective features may be formed on the second surface. It has also been observed that RRE allows an athlete to preferentially develop fast twitch muscles useful for enabling improved running speed. In a second position when activated by the pawl, the carrier latch disconnect releases the carrier latch to engage the carrier which is locked in a downward position to receive a shell from the magazine.