Apparatus and methods according to the present invention preferably utilize electroosmotic pumps that are capable of generating high pressure and flow without moving mechanical parts and the associated generation of unacceptable electrical and acoustic noise, as well as the associated reduction in reliability. The video coder employs a generalized multiple reference picture buffer which may contain multiple reference pictures in both the forward and backward temporal direction from the current picture. Antibodies against the cell surface molecules significantly ameliorate pathological conditions of autoimmune diseases and allergic diseases. A synonym service, a translation service, and a validation service analyze a new or modified relationship prior to storing the relationship in a relationship store. The user can then enter the password on the touch pad with his finger.