A test component and method of operation thereof are provided, the test component being arranged in a test environment to issue a test sequence over a bus to a device under test. These retortable containers and multilayer films are also beneficially self-venting upon exposure to microwave heating, when the internal container pressure exceeds a threshold value. Still another aspect of the present invention provides an adapter topology system, comprising an ACDC or DCDC adapter comprising circuitry to generate a signal proportional to the maximum adapter current; and a portable electronic device adapted to receive power from said adapter and to receive said signal proportional to the maximum adapter current. Given the ability of cyclincyclin-dependent kinase 2 antagonists to kill transformed cells, flavopiridol may stabilize E2F1 and enhance apoptosis via repression of Mcl-1.