The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. This utility model also disclose one kind of electronic light-emitting rings assembled with vibration light-emitting devices, the said electronic light-emitting ring is integrated silica gel, there are one opening and one cavity at the internal side of the said light-emitting ring, the said opening and cavity are connected, and the said vibration light-emitting device is set inside the cavity. When R is hydrogen the anion is unsubstituted. In a further embodiment, the processing circuitry is further operable to dim the first light source for at least a portion of the time that the sensor is being used to sense the unexposed region of the film. The trench has sidewalls that define a polygon in the plane of the substrate so that adjacent sidewalls contact one another at an angle greater than 90 degrees. Moreover, flip-chip interconnects configured in accordance with principles of the present disclosure can provide improved z-axis spacing between die-to-die andor die-to-substrate flip chip stacks, for example z-axis spacing as large as 600 \u03bcm.