A labeling reagent for use in oligonucleotide synthesis, as well as a method of preparing such a labeling reagent, a method of using such a reagent for synthesizing a labeled oligonucleotide, and an oligonucleotide prepared using such a reagent. The system may include an access port having an RFID tag with its antenna adjacent to the receiving portion of the port. The clamping structure includes clamping members arranged on the light bar, and positioning connectors arranged on the back plate at positions corresponding to the clamping members. A control mechanism is mounted to the housing and is operatively connected to the motor.