This invention relates to novel penetrating compositions including one or more effectors included within a water soluble composition, immersed in a hydrophobic medium The invention also relates to methods of treating or preventing diseases by administering such penetrating compositions to affected subjects. The developer for electrostatic image development of the invention exhibits a stable development and transfer behavior without any variation of triboelectric charging performance, electric resistance, or the like, even when used as a two-component developer, and in addition, affords a printed image with high image quality and high grade without any fogging. The first switch is arranged between the decoupling capacitor and ground.