The invention provides a monitoring device that features: 1) a cardiac sensor component with at least one light-emitting diode and a photodetector; 2) a pedometer component with at least one motion-sensing component ; and 3) a wireless component with a wireless interface that communicates with an external weight scale. The resultant film shows a high quality and an improved adhesion strength while it can be formed at a practically high rate. The present invention also relates to the processes for the preparation of novel compounds of formula and their use in treating type II diabetes and diabetic complications thereof and also for treating dislipidemia, hypercholesterolemia, obesity and hyperglycemia. The serialization system includes an identification component that identities entity associated with an item and a serialization component that serializes the item and associated entity. More specifically, novel diarylpyrimidine derivatives that are derivatives of the HIV reverse transcriptase inhibitor TMC278 of formula are provided, and pharmaceutically acceptable salts, solvates or hydrates thereof.