The present invention is directed to a modified glutamine PRPP amidotransferase and a method of using that modified enzyme to enhance the biosynthesis of purine nucleotides. The methods and compositions of the present invention may be used independently to promote andor maintain iron absorption in a patient or may be used in combination with one or more other compositions used in the treatment of one or more diseases having iron deficiency associated therewith. An enhanced target pixel value is then output according to the obtained look up table image enhancement value. The flexible film section is detachably connected, along at least one segment of its first and second lateral edges, to an additional flexible film section or one of the protective sections. The semiconductor memory device further includes a connection control circuit that connects a source terminal of the second MOSFET with the reference cell at the time of a regular operation and connects the source terminal of the second MOSFET with a reference voltage terminal at the time of a test operation. If a signature is found in the file, a reporting module sends the host file for the process and the memory dump file to a security server for analysis.