The present invention provides compositions and methods for the treatment of central nervous system damage in a subject. A conveyor moves the bottles through a fitting station below the axis and a downwardly open magazine holding a stack of the caps in a pick-off station above the axis is vertically displaceable between a lower position with the stack engageable with the seat in the pick-off station and an upper position with the stack clear of the seat in the pick-off station. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate.