An apparatus for insertion of a medical device in the skin of a subject is provided, as well as methods of inserting medical devices. While the vacuum chamber is being evacuated to a pressure of between 0. The upper storage has an upper opening for receiving and dispensing a life jacket that is retained within the upper storage by a securing strap. The thermal protection circuit includes a power conditioner for providing regulated power rails to the other components of the thermal protection circuit. Thus, an alignment failure can be reduced because a particle on the wafer is not mistaken as an alignment mark.