The present invention relates to devices and methods for securing a pair of suture lengths together or for using a single strand of suture to secure tissue together at an operative site in a patient without necessarily tying a knot. An edge pixel accommodates, in order from an edge of the image sensor toward an interior, a predetermined empty region, a photoelectric converter and a pixel circuit. Processing of the transaction triggers the first application to invoke a second application, such as an ABAP application, on a second platform. RM protection is then applied to the email with the attached RM-protected attachment based on the generated and the generated bind ID. The database also estimates aggregate co- and adjacent channel primary and secondary incumbent system interference levels at the transmitter location and predicts channel quality for each allowable channel. The projecting ledge 28 of the separable pin 6 is adapted to abut against the upper end of the projecting fin 25 of the retainer pin 5 and thus prevent the separable pin 6 from moving further into the reverse-separating slider 3.