Frame Relay connectivity is provided via point to multipoint networks. The memory control circuitry is configured to access multiple sectors of information substantially concurrently. A direct PD architecture can estimate the instantaneous frequency of a complex primary signal, iteratively adapting a phase of a complex exponential by minimizing the mean squared error of a complex error signal. The voice recognition software interprets the information and communicates it to recipient matching software. The present invention also describes methods of production of the polymer carriers and methods for the treatment or diagnosis of diseases employing the polymer carriers.