This invention relates generally to nucleic acid hybridization analysis. The methodologies involve a coordinated scheme of apparatuses that function to monitor various aspects of a creping cylinder coating so that the thickness of the coating can be determined. The serial optical signals of a first Bit-rate of several Gbits and more are converted to serial electrical signals and are multiplexed to parallel electrical signals at a lower second Bit-rate. The power for the purification module may come from batteries, solar cells, fuel cells, power converted from pumping or winding action or any combination thereof.