An image sensor package includes a housing defining a top opening, an image sensor received in the housing, and a converging lens covering the opening to hermetically seal the housing and form a window for light to pass through into the housing. Some of the information elements are mapped to corresponding parameters. The present invention describes the use of a beta-blocker in the treatment of a diabetic. Alternatively, the olefin-based copolymers of the invention can be used as an additive in a curable coating composition to provide excellent adhesion to olefinic substrates like TPO, even when used in very minor amounts compared to the amounts required for previously known agents. A plate 320 with protrusions 320 is raised into a substrate tray 100 with holes.