An agent for increasing the sugar-transporting capacity and an agent for preventing andor treating diabetes, diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic macroangiopathy, impaired glucose tolerance or adiposis, which contains a lactam compound or a pharmaceutically acceptable salt thereof as the active ingredient. The system receives a transaction for an item. The UDP is labeled by the labeling process to include at least one key property excluded from the original data. The rollup blade includes an upper electrode and at least two layers having different optical properties. Since this compound has an inhibitory action on costimulatory signal from CD28 on T cell, it is useful for the prophylaxis or suppression of rejection reaction in transplantation of organ or bone marrow and the like, and the prophylaxis or treatment of autoimmune diseases or allergic diseases.