The present invention provides a computer-assisted method for creating and displaying a model of a molecule in which residues that are affected by the binding of a ligand to the molecule are highlighted, making it possible to trace the path of propagation of a binding signal through the molecule. The laser pump source has a pulse duration that may be short enough to gain switch a particular transition or long enough to allow end-pumping with high energy densities without damage. The construction of the pressure vessel includes multiple fiber plies. 0 MPa, volume hourly space velocity of a mixture of hydrogen and carbon monoxide within the range of 100 to 5000, the mole ratio of hydrogen to carbon monoxide within the range of 1 to 4. The initial weightings or the data are unadjusted by socially responsible considerations. The modifiers confer different functionalities to base game symbols or an augmenting functionality to alter or provide an outcome.