The present invention provides novel compositions and methods for protecting and promoting cell growth and restoring physiological structure and function to mucosal tissue of the body, especially mucosa in the gastrointestinal tract. The present invention is also directed to methods for detecting a molecule that modulates Notch activation by observing or measuring a change in the amount of Notch expressed on the cell surface or a change in the amount or pattern of Notch cleavage products. The read circuit is configured to sense a resistance through a memory cell in the array of memory cells to obtain a sense result and calibrate the read circuit based on the sensed result. The video streaming application is a multi-threaded application in which a background thread performs tasks that may not require user interaction and a foreground thread performs tasks that may require user interaction. Further, test parameters obtained from the parameter testing circuits can be utilized to adjust operating parameters of the integrated circuit.