This invention relates to novel naphthopyrans having an oxygen-containing heterocyclic group F annelated on the i, j, or k side of the naphthopyran ring, having certain substituents at the 2, 5, and 6 positions of the naphthopyran ring. More particularly, the present invention provides a swallow formulation comprising paracetamol which facilitates the rapid delivery of paracetamol into the circulatory system following oral administration. An actuator is disposed within the hollow inner cylindrical core capable of movement within the cylindrical core along the axis. The first articulating joint replacement component is engaged with the second articulating joint replacement component. The guide tube’s change in axial orientation may be fixed or variable.