The present invention relates to a novel endonuclease enzyme which is secreted from immune cell and recognizes bacterial DNA as foreign agent and processes it to produce about 10 bp single-stranded oligonucleotide including CpG motif which is involved in immune response. The metod can be used, for example, for separating mixed epimers of the vitamin D analog. The switch includes, and is timely correlated with, an output switch of the digital-to- analog converter. The physical function can be a nonlinearity profile of a sample with at least one sample surface. Some embodiments of the invention provide methods and apparatuses for implanting a genetically modified DMO. The single-turn magnet provides an absolute, coarse indication of input shaft rotation with a typical accuracy of 2%.