A programmable memory controller has a main memory device, a command decoder, a period setting device, a command-sequencing device and a command signal output device. Also disclosed are pharmaceutical compositions containing said compounds and their use as thrombin receptor antagonists and binders to cannabinoid receptors. Also provided are immunogenic determinants derived from said polypeptides and antibodies raised thereto. When the electrode is energized and when fluid is delivered through the one or more fluid distribution branches from the trunk, the conductive fluid fills the fluid chamber and flows out from the chamber through the plurality of pores of the cap establishing ionic transport of ablation energy from the inner electrode to a target site in close proximity to the cap. With this, it becomes possible to generate sufficient deceleration, when the vehicle runs a downhill during cutoff-cylinder operation, while ensuring to prevent the operator to feel excessive acceleration. The patch comprising a styrene-isoprene-styrene block copolymer, polyisobutylene, tackifier, plasticizer and pharmaceutically effective ingredient, in which two or more kinds of polyisobutylene of different average molecular weight are used in combination and the viscosity of the adhesive of the patch is between 1500 and 30,000 poise and the tack of the patch is from 5 to 200 g10 mm.