A predictive routing scheme for broad band Low Earth Orbit satellite constellations is presented. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals. The embedded layer partially overlaps a high concentration drain region. The indicating device may be located on at least one of the top edge, the bottom edge, and the opposing side edges.