Fluorophore-labeled collagen covalently bound to a cell culture vessel can be used to assay collagen degradation by a variety of cell types, including osteoclasts and tumor cells. The stepped front panel has a recessed first portion and a second portion, where the second portion extends farther in a forward direction, e. The ball joint has a head and a neck. Further data collection, including changes to or refinement of collection techniques, is undertaken based on evaluations of the uncertainty.