A variable valve timing controller has a phase adjusting mechanism. A cross-sectional area between the base portion and the tip portion decreases in a substantially continuous manner in a direction from the base portion to the tip portion. Then the length and width of the original pattern are converted. The second dielectric film attracts the focus ring fitted on the flange to the holder main body by an attracting force larger than that of the first dielectric film using a Johnson-Rahbek force. Methods are also provided for the direct andor targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent. 5 cm in diameter; attractive bright yellow-colored ray florets and light green to bright yellow-colored disc florets; response time about 59 days; dark green-colored foliage; strong and thick peduncles; and excellent postproduction longevity with inflorescences and foliage maintaining good substance and color for about 21 days in an interior environment.