The subject matter of this specification can be implemented in, among other things, a computer-implemented method for application lifecycle management including providing a first application version to initial computing devices. In some implementations, cells in a biological specimen can be used for determining the mapping information between the imaging stations. The second planetary gearset includes a second sun gear, a second ring gear, and a second carrier. The shape of the surrounding area may be varied to further enhance the correction procedure. Also, lyophilized compositions that include a dried suspension, methods of making the lyophilized composition, methods of preparing the suspension, and sustained release formulations prepared by the methods.