Genes and proteins involved in the biosynthesis of benzodiazepines by microorganisms, including the genes and proteins forming the biosynthetic loci for the benzodiazepine anthramycin from Streptomyces refuineus subsp. Receivers are disclosed for receiving ancillary-service transmissions without interference-filter pre-coding, which receivers include adaptive channel-equalization filters and subsequent decoders for CCC. The second well is adjacent to the first well, and includes an insulating region and a second-type diffusion region outside the insulating region.