A method for performing Magnetic Resonance Imaging guided core biopsies is tendered more accurate and efficient by precisely positioning a disengaged probe assembly with respect to a localization fixture attached to a breast coil platform. The method includes extracting at least two image portions from at least two radiological images of an area to be treated. The aim of the invention is to provide a structure of the repeater in which the computational complexity is reduced without this reduction having a negative effect on the performance during signal filtering andor suppression of natural oscillation. The present invention also provides host cells further comprising nucleic acid encoding desired heterologous proteins such as enzymes. The protein, its partial peptide or a salt thereof has physiological activities such as a nerve-extending or nerve-regenerating activity, a gliacyte stimulating activity, and so on.