Techniques are provided for fabricating memory with metal nanodots as charge-storing elements. The invention further relates to an apparatus comprising the article, to its use and to a method of manufacturing such an article. The membrane is arranged to be a fluid contact with the perfusion fluid, while the first sheet formed organ is arranged to contact the barrier layer of the membrane, in order to simulate the dissolution of the particles in the airblood barrier when perfusion fluid flows through the perfusion chamber, along the membrane.