A high density memory device is fabricated three dimensionally in layers. The invention includes authoring software to create a data structure and to populate the created data structure with obtained metadata. When a voltage having a lower electric potential than the collector electrode is applied to the trench gate electrode at that time, p-type carriers are generated within the cathode and a quantity of carriers increases within the return diode. The processor collects time series of amplified electric field and magnetic signals over a predetermined period of time. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory effect in a warm-blooded animal, such as man. The first circuit may be configured to generate a first reference signal in response to a pump-up signal and a second reference signal in response to a pump-down signal.