A file attachment processing method and system. The method, in one embodiment, includes forming semiconductor features over a substrate, and then forming a layer of material over the semiconductor features. The cavity encloses an element on which two valve bodies are formed. Additionally or alternatively, the reinforcing fiber, in particular quartz fiber, has a hardness of at least about 4 on the Mohs scale, as measured on bulk material, which resists cutting by an impacting object. The histamine-mediated condition may be an allergic shock, septic shock, allergic asthma, anaphylaxis, rhinitis, allergic conjunctivitis, urticaria, atopic dermatitis, and pruritus.