The present invention relates to compositions and methods for the prevention, prognostic evaluation, and treatment of oncogenic disorders, especially breast cancer, wherein a protein tyrosine kinase capable of complexing with a member of the SH2- andor SH3-containing family of adaptor proteins is involved. The riser includes a portion extending in a longitudinal direction of the riser. The first, fixed blade is provided by the pointed lower end of the shaft. Upon transitioning into the boost mode, the duty cycle of the boost power switch is immediately reduced to compensate for the buck switching being stopped and the buck power switch having a minimum off-time.