The invention provides a decolonizing agent that can effectively decolonize Helicobacter pylori. Defect density is the number of distinct defects which required changes to be made to a particular file or module in a given period of time. The diagnostic system also includes either a discharge pressure sensor or a condenser temperature sensor, an ambient air sensor and a voltage sensor. When the grinding stone portion is put into rotational contact with a workpiece, the workpiece is ground through to form a circle hole in section leaving a cylindrical core therein. The coating layer formed on the inorganic material layer is made from titanium aluminum nitride. Next, the photoresist is removed from the optical coating to expose the gettering agent in the trenches.