Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e. The liner’s mass and stiffness are tuned to attenuate one or more of a bending mode vibration and a torsion mode vibration that occurs at a first predetermined frequency. These constructs are useful for modifying microbial strains to improve production and recovery processes for polymers such as intracellular proteins, such as enzymes, growth factors, and cytokines; for producing polyhydroxyalkanoates; and for producing extracellular polysaccharides, such as xanthan gum, alginates, gellan gum, zooglan, hyaluronic acid and microbial cellulose. An insulating layer then fills the remaining portions of the cavity. The first pairs of connector terminals are mounted on one side of the board in first pairs of terminal openings, and the second pairs of connector terminals are mounted on the opposite side of the board in second pairs of terminal openings which are electrically connected to the first pair of openings. The GM-CSF may be administered concurrently with at least one antiretroviral agent.